Biology

A.Y. 2020/2021
6
Max ECTS
48
Overall hours
SSD
BIO/13
Language
Italian
Learning objectives
The course is designed to provide students with the basic knowledge of animal Biology. The course will then be specifically focused on eukaryotic cells. Students will acquire knowledge on: structure and function of the cell, biological membranes, subcellular organelles, cell metabolism, the flow of the genetic information into the cell (gene, eukaryotic genome, DNA replication, transcription, translation, control of gene expression). Additional objectives of the course will be to provide students with the knowledge of the mechanisms of cell proliferation and cell cycle checkpoints, cell death, cell-to-cell communication, mitosis, meiosis and the principles of heredity (Mendelian heredity). This course will provide students with the basic scientific knowledge necessary to face the courses of the following years.
Expected learning outcomes
At the end of the Course, students should prove that they have acquired and understood the knowledge of the main biological features of animal cells (eukaryotic cells). Specifically, they should have acquired and understood the basic knowledge on the structure and biological features of animal cells: cell membrane, cytoplasmic organelles, metabolism, flow of the genetic information, cell life/death programs, cell-cell interactions, asexual/sexual reproduction, transmission and expression of hereditary traits (Mendelian law of inheritance).
At the end of the Course students should have acquired an accurate and specific biological language allowing them to communicate the specific knowledge.
Course syllabus and organization

Single session

Responsible
Lesson period
First semester
Teaching methods
The lessons will be held on the Microsoft Teams platform and can be followed either synchronously based on the timetable of the first semester, or asynchronously because they will be recorded and left available to students on the same platform.

Program and reference material
The program and reference material will not be changed.

Assessment methods
The exam will consist of an oral interview, using the Microsoft Teams platform.
Course syllabus
Program for attending and not attending students.
Origin of life - Prokaryotes and Eukaryotes - Atoms and Chemical bonds - Carbohydrates, lipids, amino acids, nucleotides, proteins and enzyme structure - Plasmatic membrane - Transport mechanisms across plasmatic membrane - The system of intracellular membranes - The endoplasmic reticulum (ER), the Golgi Apparatus, lysosomes and peroxysomes - Intracellular compartments and vesicle transport - Energy and cellular metabolism -The mitochondria -The nucleus - Chromatin and chromosomes - DNA structure and DNA replication - Transcription, RNA processing - Protein translation - Mechanisms of gene expression -The cytoskeleton -Extracellular matrix - Junctions between the cells - Cell communication and signalling - The cell cycle and its control - Mitosis - Cancer cell - Meiosis - General aspects of mechanisms of fertilisation - Mendelian inheritance
Prerequisites for admission
There are not specific prerequisites other than those required for access to the course.
Teaching methods
Lecture classes with the support of slides.
Teaching Resources
- Cooper G.M. e Hausman R.E.
La cellula - Un approccio molecolare - Piccin
-Alberts
L'essenziale di biologia molecolare - Zanichelli

Slides of the lessons: available at the teacher's site in Ariel (http://users.unimi.it/ariel)
Assessment methods and Criteria
The exam is oral and is based on the discussion of all the topics addressed during the lecture classes of the course. Students will be asked to demonstrate to have acquired knowledge of the main biological features of animal cells (eukaryotic). Specifically, they should demonstrate to have acquired a solid knowledge on: cell membranes, enzymes, cytoplasmic organelles, cell metabolism, flow of the genetic information from DNA to proteins, cell life/death programs, cell-cell interactions and communications, mitosis and meiosis, asexual/sexual reproduction, basis of human genetics, Mendelian inheritance, molecular basis of cellular transformation (tumorigenesis). During the examination, students should demonstrate to have acquired an accurate and specific biological language allowing them to communicate the most relevant topics in the field of biology.
The evaluation of the oral exam will be expressed in thirtieths (from 18/30 to 30/30).
BIO/13 - EXPERIMENTAL BIOLOGY - University credits: 6
Lessons: 48 hours
Professor: Crippa Valeria
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