Molecular and cellular biology

Doctoral programme (PhD)
A.Y. 2019/2020
Study area
Science and Technology
Doctoral programme (PhD)
Dipartimento di Bioscienze - Via Celoria, 26 - Milano
PhD Coordinator
The doctoral programme aims to:
- train scientific experts with excellent skills in the field of biomolecular sciences and biotechnology;
- promote a molecular approach to the study of complex biological problems in model organisms (prokaryotic and eukaryotic microorganisms, animals and plants);
- encourage collaboration between research institutes, advanced training schools and companies in the fields of biomolecular sciences and biotechnology;
- encourage internationalisation by promoting international scientific collaborations, involving foreign lecturers, recruiting postgraduate students from abroad, and organising co-tutored dissertations involving study periods abroad.
Training activities will be characterised by:
- a multidisciplinary approach;
- interactivity;
- links to the business world;
- internationalisation.
A key element of the programme is the direct involvement of doctoral students in experimental research activities. Students will work full-time on a research project, providing critical insight and suggestions, and thereby acquiring scientific and organisational independence.
Classi di laurea:
LM-6 Biologia,
LM-7 Biotecnologie agrarie,
LM-8 Biotecnologie industriali,
LM-9 Biotecnologie mediche, veterinarie e farmaceutiche,
LM-11 Conservazione e restauro dei beni culturali,
LM-13 Farmacia e farmacia industriale,
LM-17 Fisica,
LM-18 Informatica,
LM-21 Ingegneria biomedica,
LM-22 Ingegneria chimica,
LM-25 Ingegneria dell'automazione,
LM-31 Ingegneria gestionale,
LM-32 Ingegneria informatica,
LM-35 Ingegneria per l'ambiente e il territorio,
LM-40 Matematica,
LM-41 Medicina e chirurgia,
LM-42 Medicina veterinaria,
LM-44 Modellistica matematico-fisica per l'ingegneria,
LM-46 Odontoiatria e protesi dentaria,
LM-47 Organizzazione e gestione dei servizi per lo sport e le attività motorie,
LM-48 Pianificazione territoriale urbanistica e ambientale,
LM-51 Psicologia,
LM-52 Relazioni internazionali,
LM-53 Scienza e ingegneria dei materiali,
LM-54 Scienze chimiche,
LM-56 Scienze dell'economia,
LM-58 Scienze dell'universo,
LM-59 Scienze della comunicazione pubblica, d'impresa e pubblicità,
LM-60 Scienze della natura,
LM-61 Scienze della nutrizione umana,
LM-67 Scienze e tecniche delle attività motorie preventive e adattate,
LM-68 Scienze e tecniche dello sport,
LM-69 Scienze e tecnologie agrarie,
LM-70 Scienze e tecnologie alimentari,
LM-71 Scienze e tecnologie della chimica industriale,
LM-73 Scienze e tecnologie forestali ed ambientali,
LM-74 Scienze e tecnologie geologiche,
LM-75 Scienze e tecnologie per l'ambiente e il territorio,
LM-76 Scienze economiche per l'ambiente e la cultura,
LM-78 Scienze filosofiche,
LM-79 Scienze geofisiche,
LM-82 Scienze statistiche,
LM-86 Scienze zootecniche e tecnologie animali,
LM-91 Tecniche e metodi per la società dell'informazione,
LM-92 Teorie della comunicazione,
LM/SNT1 Scienze infermieristiche e ostetriche,
LM/SNT2 Scienze riabilitative delle professioni sanitarie,
LM/SNT3 Scienze delle professioni sanitarie tecniche,
LM/SNT4 Scienze delle professioni sanitarie della prevenzione
Dipartimento di Bioscienze - Via Celoria, 26 - Milano
Title Professor(s)
From protein structure to novel therapeutics against rare genetic diseases
Immunoregulation in the tumor microenvironment
Characterization of the Genetic Basis of the Pawpaw (Asimina triloba) Domestication
Characterisation of MIZ1-ECA1 interaction to shed light on the mechanisms underlying long-distance Ca2+ signalling in plants
Exploiting Escherichia coli to understand the molecular defects of disease-linked polynucleotide phosphorylase (hPNPase) variants
Integrating pathogen genomes and health big data for challenging health-associated infections
Microtubule dysfunction and neurodegeneration: dissecting the interplay of alpha-synuclein with tubulin in models of Parkinson's disease"
Molecular modelling of biomolecular self-assembly processes
In vivo modelling of liver cancer to resolve the chromatin dependencies of intestinal dysbiosis
M. Cassano
Huntington’s Disease: biological and molecular aspects in neurons and glia derived from pluripotent stem cells
E. Cattaneo
Differentiation of germline in plants
Molecular and genetic control of plant reproduction and seed development
Integration of drought and phyto-hormonal signals at the shoot apical meristem of plants
Harnessing the new emerging imaging technologies to uncover the role of Ca2+ signaling in plant nutrient homeostasis
Study of NF-Y expression across TCGA cancer datasets
Defining the molecular and cellular mechanisms by which tissue macrophages promote angiogenesis in neovascular diseases
Uncoupling flowering from internode elongation during the floral transition of rice
Dissecting the role of nfy “mirnome” in human cancer
Functional Analysis of Genes Controlling Inflorescence Architecture in Arabidopsis and Rice
Role of c-di-GMP and other nucleotide-derived signal molecules in Crohn’s disease-associated host-bacteria interaction
Smpx-deficient zebrafish embryos: a tool for studying human hearing loss
Transcription Factor Partnerships in the Regulation of ER-stress Response Genes
Study of the antiproliferative effect of metformin combined to transcranial stimulation in glioblastoma cellular and animal models
Development of genetic and pharmacological approaches to cure Muscular Dystrophies
Engineering of synthetic protein tools for optogenetics
Biophysical and structural (NMR and crystallography) characterization of the transcription factor Nf1x involved in muscular dystrophy
Accumulation of replication/repair intermediates as a cause for genomic instability: integrated in vivo and in silico studies
SOUP: Signaling the Organelle Unfolded Protein response
Envelope biogenesis in Gram-negative bacteria as molecular target for the development of next generation antibacterial drugs
Exploiting the CRISPR-Cas9 technology to study the double strand DNA break repair and genome stability
L. Popolo
Dissecting the molecular bases of Human Light Chains “soluble toxicity”
USP36, a novel repressor of Notch signaling in human cells
Development and implementation of cloud-oriented bioinformatic tools and workflows
Unveiling the AIEC-antigens and gut-microbiota species involved in modulation of pathogenic Th1/17 cells differentiation and activation in Crohn’s disease
Neurobiology of parkinsonism

Courses list

Courses or activities Professor(s) ECTS Total hours Language
Molecular and cellular biology. methods and communication of results
4 24 English
Courses or activities Professor(s) ECTS Total hours Language
Ribosomal biology and translational control. a theoretical and practical approach
3 15 English
Courses or activities Professor(s) ECTS Total hours Language
Introduction to transcriptomic data analysis
6 30 English
Courses or activities Professor(s) ECTS Total hours Language
Virology: new advances in basic and applied research
2 15 English
Courses or activities Professor(s) ECTS Total hours Language
How to write a molecular and cellular paper
4 20 English
Courses or activities Professor(s) ECTS Total hours Language
Introduction to Explorative Data Analysis in R
2 12 Italian