The course will endow the students with theoretical as well as practical knowledge of cell population dynamics in animal biology. I will focus on examples of concerted cell behaviors that have been biophysically-characterized and/or mathematically modeled. Several aspects of cell populations will be considered and covered: movements, rearrangements, concerted signaling and gene expression. Hands-on activities in the teaching lab will focus on examples of cell polarization and migration in tissue culture, as well as cell rearrangements in vivo using Drosophila melanogaster as a model.
Risultati apprendimento attesi
Students will acquire understanding of the state of the art in studying behaviors of cell populations. In particular: -they will learn the techniques utilized to visualize cell changes, both those involving averaging and those describing single cells. - they will be able to select the appropriate system and apply the correct set of descriptors to answer typical quantitative questions in the field of cell and tissue biology. -they will develop a critical capacity to evaluate relevant experimental examples provided by published studies. -they will practice communication of the qualitative and quantitative aspects of relevant studies keeping in mind different target audiences.
Periodo: Secondo semestre
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